M. Cuchel: search on Z-Library

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1

Clinical Genetic Testing for Familial Hypercholesterolemia

Sturm, Amy C., Knowles, Joshua W., Gidding, Samuel S., Ahmad, Zahid S., Ahmed, Catherine D., Ballantyne, Christie M., Baum, Seth J., Bourbon, Mafalda, Carrié, Alain, Cuchel, Marina, de Ferranti, Sarah

Journal:

Journal of the American College of Cardiology

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

2

Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society Severe Familial Hypercholesterolemia Panel

Santos, Raul D, Gidding, Samuel S, Hegele, Robert A, Cuchel, Marina A, Barter, Philip J, Watts, Gerald F, Baum, Seth J, Catapano, Alberico L, Chapman, M John, Defesche, Joep C, Folco, Emanuela, Freibe

Journal:

The Lancet Diabetes & Endocrinology

Year:

2016

Language:

english

File:

PDF, 316 KB

english, 2016

3

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

Khera, Amit V., Cuchel, Marina, de la Llera-Moya, Margarita, Rodrigues, Amrith, Burke, Megan F., Jafri, Kashif, French, Benjamin C., Phillips, Julie A., Mucksavage, Megan L., Wilensky, Robert L.

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 601 KB

english, 2011

4

Longitudinal Evaluation and Assessment of Cardiovascular Disease in Patients With Homozygous Familial Hypercholesterolemia

Daniel M. Kolansky, Marina Cuchel, Bernard J. Clark, Steve Paridon, Brian W. McCrindle, Susan E. Wiegers, Luis Araujo, Yogesh Vohra, Joep C. Defesche, James M. Wilson, Daniel J. Rader

Journal:

The American Journal of Cardiology

Year:

2008

Language:

english

File:

PDF, 135 KB

english, 2008

5

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

Wiegman, Albert, Gidding, Samuel S., Watts, Gerald F., Chapman, M. John, Ginsberg, Henry N., Cuchel, Marina, Ose, Leiv, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Albe

Journal:

European Heart Journal

Year:

2015

Language:

english

File:

PDF, 918 KB

english, 2015

6

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., Trompet, S., Jukema, J. W., De Craen, A.,

Journal:

Year:

2016

Language:

english

File:

PDF, 966 KB

english, 2016

7

Recognition, diagnosis and treatment of homozygous familial hypercholesterolemia

Ajufo, Ezim, Cuchel, Marina

Journal:

Expert Opinion on Orphan Drugs

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

8

Target achievement and cardiovascular event rates with Lomitapide in homozygous Familial Hypercholesterolaemia

Blom, Dirk J., Cuchel, Marina, Ager, Miranda, Phillips, Helen

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 359 KB

english, 2018

9

Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement

Hegele, Robert A, Borén, Jan, Ginsberg, Henry N, Arca, Marcello, Averna, Maurizio, Binder, Christoph J, Calabresi, Laura, Chapman, M John, Cuchel, Marina, von Eckardstein, Arnold, Frikke-Schmidt, Ruth

Journal:

The Lancet Diabetes & Endocrinology

Year:

2019

Language:

english

File:

PDF, 3.85 MB

english, 2019

10

Determination of Lp(a) and APO(a) in an Italian population

Marina Cuchel, Giuliana Merati, Marigrazia Clerici, Bruno Grumelli, Gino Alberto Giudici, Carlo Vergani

Journal:

International Journal of Clinical & Laboratory Research

Year:

1991

Language:

english

File:

PDF, 594 KB

english, 1991

11

Treatment of Familial Hypercholesterolemia: Is There a Need Beyond Statin Therapy?

Anna Raper, Daniel M. Kolansky, Marina Cuchel

Journal:

Current Atherosclerosis Reports

Year:

2012

Language:

english

File:

PDF, 126 KB

english, 2012

12

Inflammation induces fibrinogen nitration in experimental human endotoxemia

Sean P. Heffron, Ioannis Parastatidis, Marina Cuchel, Megan L. Wolfe, Mahlet G. Tadesse, Emille R. Mohler III, Harry Ischiropoulos, Daniel J. Rader, Muredach P. Reilly

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

13

The Effects of a Microsomal Triglyceride Transfer Protein Inhibitor on Fat Soluble Compounds

L.T. Bloedon, M. Cuchel, T. Santoroski, W. Sasiela, D.J. Rader

Journal:

Journal of the American Dietetic Association

Year:

2007

Language:

english

File:

PDF, 33 KB

english, 2007

14

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

A.V. Khera, M. Cuchel, M. de la Llera-moya

Journal:

Journal of Vascular Surgery

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

15

Impact of hydrogenated fat consumption on endogenous cholesterol synthesis and susceptibility of low-density lipoprotein to oxidation in moderately hypercholesterolemic individuals

Marina Cuchel, Ursula S. Schwab, Peter J.H. Jones, Silke Vogel, Carol Lammi-Keefe, Zhengling Li, Jose Ordovas, Judith R. McNamara, Ernst J. Schaefer, Alice H. Lichtenstein

Journal:

Year:

1996

Language:

english

File:

PDF, 818 KB

english, 1996

16

Atherogenic lipid profile in elderly patients with ischaemic cerebrovascular disease

Marina Cuchel, David J Stott, Allan Gaw, Carlo Vergani, Chris J Packard

Journal:

Year:

2000

Language:

english

File:

PDF, 57 KB

english, 2000

17

Cholesterol and all-cause mortality in Honolulu

Marina Cuchel, Daniel J Rader

Journal:

Year:

2001

Language:

english

File:

PDF, 164 KB

english, 2001

18

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

Cuchel, Marina, Meagher, Emma A, du Toit Theron, Hendrik, Blom, Dirk J, Marais, A David, Hegele, Robert A, Averna, Maurizio R, Sirtori, Cesare R, Shah, Prediman K, Gaudet, Daniel, Stefanutti, Claudia,

Journal:

Year:

2013

Language:

english

File:

PDF, 222 KB

english, 2013

19

Tu-PL2:2 Molecular and pharmacologic regulation of reverse cholesterol transport

Rader, D.J., Wang, X., Tohyama, J., Tanigawa, H., Collins, H., Cuchel, M., Fuki, I., Billheimer, J., Rothblat, G.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

20

Tu-W23:5 Intravenous administration of large unilamellar vesicles and Apo AI/Phospholipid complexes increases free cholesterol in plasma by different mechanism

Cuchel, M., Lund-Katz, S., De La Llera-Moya, M., Rothblat, G.H., Phillips, M.C., Rader, D.J.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

21

Abstract: 1460 LOWERING LDL THROUGH MTP INHIBITION

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

22

Abstract: P471 IMPACT OF THE MTP-INHIBITOR AEGR-733 ON THE SINGLE-DOSE PHARMACOKINETICS OF EXTENDED-RELEASE NIACIN

Dunbar, R, Bloedon, L, Gadi, R, Movva, R, Baer, A, Parris, M, Sasiela, W, Rader, D, Cuchel, M

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 85 KB

english, 2009

23

Abstract: P469 IMPACT OF HIGH DOSES OF THE MTP-INHIBITOR, AEGR-733, ON THE SINGLE DOSE PHARMACOKINETICS OF ATORVASTATIN AND ROSUVASTAIN

Dunbar, R, Bloedon, L, Gadi, R, Duffy, D, Baer, A, Sasiela, W, Rader, D, Cuchel, M

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 85 KB

english, 2009

24

L5 PHASE 3 STUDY OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR (MTP-I) LOMITAPIDE IN SUBJECTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH): 56-WEEK RESULTS

Cuchel, M., Meagher, E., Marais, A.D., Blom, D.J., du Toit Theron, H., Shah, P.K., Hegele, R.A., Bloeden, L.T., Sasiela, W.J., Rader, D.J.

Journal:

Atherosclerosis Supplements

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

25

Is the Cholesteryl Ester Transfer Protein Proatherogenic or Antiatherogenic in Humans?

Marina Cuchel, Daniel J. Rader

Journal:

Journal of the American College of Cardiology

Year:

2007

Language:

english

File:

PDF, 63 KB

english, 2007

26

The frequency of the cholesteryl ester transfer protein-TaqI B2 allele is lower in African Americans than in Caucasians

Marina Cuchel, Megan L. Wolfe, Andrew S. deLemos, Daniel J. Rader

Journal:

Atherosclerosis

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

27

2.P.271 High plasma Lp(a) levels and low plasma HDL-cholesterol levels as risk factors for cerebrovascular disease in elderly men and women

M. Cuchel, D. Stott, L. Bell, A. Gaw, M. McConnell, J. Shepherd, C.J. Packard, C. Vergani

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 186 KB

english, 1997

28

High-density lipoproteins: A consensus statement from the National Lipid Association

Toth, Peter P., Barter, Philip J., Rosenson, Robert S., Boden, William E., Chapman, M. John, Cuchel, Marina, D'Agostino, Ralph B., Davidson, Michael H., Davidson, W. Sean, Heinecke, Jay W., Karas, Ric

Journal:

Journal of Clinical Lipidology

Year:

2013

Language:

english

File:

PDF, 4.23 MB

english, 2013

29

Gene Sequencing in US Patients with Severe Clinical Familial Hypercholesterolemia∗

Schoen, Marisa, deGoma, Emil, Stef, Martianne, Cuchel, Marina, Rader, Daniel

Journal:

Journal of Clinical Lipidology

Year:

2014

Language:

english

File:

PDF, 194 KB

english, 2014

30

Apheresis Treatment did not Impact the Efficacy of Lomitapide in Patients with Homozygous Familial Hypercholesterolemia: Results from the Pivotal Phase†

Cuchel, Marina, Meagher, Emma A., Shah, Prediman Krishan, Bloedon, LeAnne T., Rader, Daniel J.

Journal:

Journal of Clinical Lipidology

Year:

2013

Language:

english

File:

PDF, 59 KB

english, 2013

31

Severe Hypertriglyceridemia and Recurrent Pancreatitis In a Patient With SLE and an Underlying Mutation in the Lipase Maturation Factor-1 Gene*

Singh, Amita, Milne, Vanessa, Cuchel, Marina, Fisher, Edward, Underberg, James, Hegele, Robert

Journal:

Journal of Clinical Lipidology

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

32

4415666 Enzyme electrode membrane

Singh, Amita, Milne, Vanessa, Cuchel, Marina, Fisher, Edward, Underberg, James, Hegele, Robert

Journal:

Biotechnology Advances

Year:

1983

Language:

english

File:

PDF, 50 KB

english, 1983

33

Lipid-lowering treatment for homozygous familial hypercholesterolaemia – Authors' reply

Cuchel, Marina, Rader, Daniel J

Journal:

Year:

2013

Language:

english

File:

PDF, 38 KB

english, 2013

34

Abstract: S3-35 CHOLESTEROL FLUX BETWEEN CELLS AND LIPOPROTEINS

Rothblat, G, Moya, M, Rader, D, Cuchel, M

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

35

Th-P16:322 Microsomial transfer protein (MTP) inhibition substantially reduces cholesterol in patients with homozygous familial hypercholesterolemia

Cuchel, M., Bloedon, L.T., Kolansky, D.M., Szapary, P.O., Wolfe, M.L., Millar, J.S., Ikewaki, K., Siegelman, E.S., Gregg, R.E., Rader, D.J.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

36

Abstract: S4-7 MTP INHIBITION FOR THE TREATMENT OF FAMILIAL HYPERCHOLESTEROLEMIA

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

37

Chronic low dose eptastigmine in Alzheimer patients: Relationship between acetylcholinesterase inhibition and cognitive effects

Anthanont, Pimjai, Polisecki, Eliana, Asztalos, Bela F., Diffenderfer, Margaret R., Barrett, P. Hugh R., Millar, John S., Billheimer, Jeffrey, Cuchel, Marina, Rader, Daniel J., Schaefer, Ernst J.

Journal:

Neurobiology of Aging

Year:

1994

Language:

english

File:

PDF, 213 KB

english, 1994

38

A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production

Anthanont, Pimjai, Polisecki, Eliana, Asztalos, Bela F., Diffenderfer, Margaret R., Barrett, P. Hugh R., Millar, John S., Billheimer, Jeffrey, Cuchel, Marina, Rader, Daniel J., Schaefer, Ernst J.

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 323 KB

english, 2014

39

Management of Aminotransferase Elevations Observed in a Phase 3 Study of Patients with Homozygous Familial Hypercholesterolemia Treated with Lomitapide

Cuchel, Marina, Meagher, Emma A., Shah, Prediman Krishan, Bloedon, LeAnne T., Rader, Daniel J.

Journal:

Journal of Clinical Lipidology

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

40

Clinical experience of lomitapide therapy in patients with homozygous familial hypercholesterolaemia

Cuchel, Marina, Blom, Dirk J., Averna, Maurizio R.

Journal:

Atherosclerosis Supplements

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

41

Pharmacokinetic Interactions of the Microsomal Triglyceride Transfer Protein Inhibitor, Lomitapide, with Drugs Commonly Used in the Management of Hypercholesterolemia

Tuteja, Sony, Duffy, Danielle, Dunbar, Richard L., Movva, Rajesh, Gadi, Ram, Bloedon, LeAnne T., Cuchel, Marina

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2014

Language:

english

File:

PDF, 174 KB

english, 2014

42

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nordestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjaerg-Hansen, A., Watts, G.

Journal:

European Heart Journal

Year:

2014

Language:

english

File:

PDF, 1.18 MB

english, 2014

43

Loss-of-Function Mutations in ABCA1 and Enhanced β-Cell Secretory Capacity in Young Adults

Rickels, Michael R., Goeser, Eugen S., Fuller, Carissa, Lord, Christine, Bowler, Anne M., Doliba, Nicolai M., Hegele, Robert A., Cuchel, Marina

Journal:

Year:

2015

Language:

english

File:

PDF, 969 KB

english, 2015

44

Long-term clinical results of microsomal triglyceride transfer protein inhibitor use in a patient with homozygous familial hypercholesterolemia

Raper, Anna, Kolansky, Daniel M., Sachais, Bruce S., Meagher, Emma A., Baer, Amanda L., Cuchel, Marina

Journal:

Journal of Clinical Lipidology

Year:

2015

Language:

english

File:

PDF, 429 KB

english, 2015

45

Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics

Larach, Daniel B, Cuchel, Marina, Rader, Daniel J

Journal:

Clinical Lipidology

Year:

2013

Language:

english

File:

PDF, 712 KB

english, 2013

46

Reconstituted High-Density Lipoprotein Therapies: A Cause for Optimism

Javaheri, A., Kolansky, D. M., Cuchel, M.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2014

Language:

english

File:

PDF, 917 KB

english, 2014

47

The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages

de la Llera-Moya, M., Drazul-Schrader, D., Asztalos, B. F., Cuchel, M., Rader, D. J., Rothblat, G. H.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2010

Language:

english

File:

PDF, 684 KB

english, 2010

48

Microsomal transfer protein inhibition in humans

Cuchel, Marina, Rader, Daniel J.

Journal:

Current Opinion in Lipidology

Year:

2013

Language:

english

File:

PDF, 192 KB

english, 2013

49

Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

Zhang, H., Xue, C., Shah, R., Bermingham, K., Hinkle, C. C., Li, W., Rodrigues, A., Tabita-Martinez, J., Millar, J. S., Cuchel, M., Pashos, E. E., Liu, Y., Yan, R., Yang, W., Gosai, S. J., VanDorn, D.

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 2.61 MB

english, 2015

50

High-Density Lipoprotein (HDL) Phospholipid Content and Cholesterol Efflux Capacity Are Reduced in Patients With Very High HDL Cholesterol and Coronary Disease

Agarwala, A. P., Rodrigues, A., Risman, M., McCoy, M., Trindade, K., Qu, L., Cuchel, M., Billheimer, J., Rader, D. J.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2015

Language:

english

File:

PDF, 885 KB

english, 2015

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